How to Prevent Medication Errors During Care Transitions and Discharge

How to Prevent Medication Errors During Care Transitions and Discharge

Health & Wellness

Dec 7 2025

13

Medication errors during care transitions aren’t rare mistakes-they’re predictable failures

Every year, over 800,000 medication errors happen when patients move between hospitals, nursing homes, or home care. Most of these errors occur during discharge. A patient leaves the hospital with a new prescription, but the community pharmacist doesn’t know about a drug they were taking at home. Or worse-they get two pills that interact dangerously because no one checked. These aren’t hypothetical risks. They’re happening right now, in hospitals across New Zealand, the U.S., and Europe. And the worst part? Most of them are completely preventable.

What exactly is medication reconciliation?

Medication reconciliation isn’t just writing down a list of drugs. It’s a formal process to make sure the medications a patient is actually taking match what’s being ordered at every point of care. This happens at admission, during transfers between units, and especially at discharge. The goal? Catch mismatches before they cause harm.

Here’s how it works in practice: A pharmacist or nurse sits down with the patient and asks, “What pills do you take every day, and how much?” They don’t just trust what’s in the chart. They call the patient’s pharmacy, check family members’ memories, even look at pill bottles. Then they compare that list to what the hospital says the patient should be on. If there’s a difference-say, the patient was on warfarin at home but the hospital stopped it without telling anyone-that’s a red flag. That’s when someone intervenes.

Why do errors happen during discharge?

Discharge is the most dangerous moment. Patients are tired. Doctors are rushed. Paperwork piles up. And the system is broken in three key ways.

  • Information doesn’t move. Only 37% of U.S. hospitals can electronically share medication lists with community pharmacies. In New Zealand, the situation isn’t much better. If a patient goes home to Dunedin after being treated in Auckland, their GP might not get the updated list for days-or ever.
  • Doctors don’t verify. A 2023 AHRQ survey found 63% of hospitals say physicians resist reconciliation because it feels like extra work. So they click ‘approve’ on a pre-filled list without checking.
  • Patient input is ignored. Only 28% of facilities consistently ask patients to confirm their own meds. But patients know what they’re taking better than anyone. One man in Wellington came home with a new blood thinner after heart surgery. He’d been on aspirin for 15 years. No one asked. He ended up in the ER with internal bleeding.

Technology helps-but it’s not a magic fix

Hospitals spend millions on electronic health records (EHRs), barcode scanners, and clinical decision tools. And yes, they’ve cut errors by nearly half in some settings. But here’s the catch: when new systems roll out, errors often spike first. A 2021 JAMA study found EHRs increased medication discrepancies by 18% during early implementation. Why? Because staff were trained to use the tool, not to think critically. They copied and pasted old lists without questioning them.

Technology works best when it supports people-not replaces them. Barcode scanning at the bedside cuts wrong-drug errors by 48%. But if the barcode doesn’t match what’s in the patient’s hand, the system fails. AI tools like MedWise Transition, cleared by the FDA in 2024, can scan a patient’s entire history and flag dangerous interactions. In a 12-hospital pilot, they reduced discrepancies by 41%. But they still need a pharmacist to review the alerts.

A pharmacist walking through a hallway of dissolving medical records and glowing EHR screens, symbolizing communication breakdowns.

Pharmacists are the secret weapon

When pharmacists lead discharge reconciliation, things change. A 2023 study in the Journal of the American Pharmacists Association found hospitals with dedicated transition pharmacists saw 57% fewer medication errors after discharge-and 38% fewer readmissions within 30 days.

Why? Pharmacists don’t just check lists. They ask: “Can you afford this?” “Do you know why you’re taking this?” “What happened last time you missed a dose?” They spot duplicate drugs, wrong doses, interactions with supplements. One pharmacist in Christchurch caught a patient being prescribed both simvastatin and clarithromycin-a combo that can cause fatal muscle damage. She called the doctor before the discharge papers were signed.

Facilities with full-time transition pharmacists report 53% fewer adverse drug events. And the best part? Pharmacists love this work. In a 2023 survey, 89% said preventing harm made them feel proud. One said: “Catching a duplicate anticoagulant order that would have caused a major bleed? That’s why I do this.”

What actually works in real hospitals?

There’s no single solution. But the most effective programs combine three things: people, process, and time.

  1. Assign clear roles. Who does the reconciliation? The nurse? The pharmacist? The resident? If it’s unclear, staff make assumptions-and mistakes. The MARQUIS study found that when roles weren’t defined, harmful discrepancies went up by 15%.
  2. Build time into the workflow. Experts say you need 15-20 minutes per patient to do reconciliation right. Most hospitals give 8-10. That’s not enough. One hospital in Dunedin started blocking 20-minute slots on discharge nurses’ calendars. Within six months, medication errors dropped by 42%.
  3. Use the MATCH toolkit. Developed by the Agency for Healthcare Research and Quality (AHRQ), this isn’t software. It’s a step-by-step guide for teams. It covers everything from how to talk to families to how to train staff. Hospitals that followed all 159 recommendations cut errors by 63%. Those relying only on EHRs? Just 41%.

Patients need to be part of the solution

Only 28% of facilities involve patients in reconciliation. That’s a huge gap. Patients know their own bodies. They remember side effects. They know if they stopped a pill because it made them dizzy.

Start simple. Give patients a printed list before discharge. Say: “This is what you’re supposed to take. Does this match what you were taking before?” Then ask them to bring the actual bottles to their follow-up. A Kaiser Family Foundation survey found that 85% of patients who participated in this process felt more confident about their meds. Only 72% understood why it mattered-but that’s a gap we can fix with education, not technology.

A patient at a hospital door holding a glowing medication list, with shadowy figures reaching from different dimensions.

Regulations are catching up

It’s no longer optional. The Joint Commission requires medication reconciliation at admission, transfer, and discharge. In the U.S., hospitals that don’t comply risk losing 0.5-1.5% of Medicare payments. Australia and the EU have similar rules. In 2025, the National Patient Safety Goals will require verification from at least two sources for high-risk drugs like blood thinners and insulin.

But rules alone don’t save lives. Implementation does. The WHO’s Medication Without Harm campaign aims to cut severe harm by 30% in high-risk transitions by 2027. That’s ambitious. But possible-if we stop treating reconciliation as paperwork and start treating it as care.

What you can do right now

If you’re a patient or caregiver:

  • Bring a list of every medication you take-including vitamins, herbs, and over-the-counter pills-to every appointment.
  • Ask: “Is anything being added, changed, or stopped today?”
  • Don’t assume the hospital will tell your GP. Follow up with them within a week.

If you’re a healthcare worker:

  • Start small. Pick one discharge unit and assign a pharmacist to lead reconciliation.
  • Use the MATCH toolkit. Don’t just install software-change how your team works.
  • Track your error rates before and after. If they drop, scale it.

It’s not about blame-it’s about systems

Medication errors during transitions aren’t caused by bad people. They’re caused by broken systems. Rushed staff. Poor communication. Fragmented records. Outdated workflows.

But we know how to fix it. We have the tools. We have the evidence. We have the experts. What’s missing is consistent action. Every time a patient leaves the hospital with a safe, accurate medication list, we prevent a trip to the ER, a longer hospital stay, or worse. That’s not just good practice. It’s the bare minimum of care.

What is the most common cause of medication errors during discharge?

The most common cause is a breakdown in communication between providers. When a hospital doesn’t share an updated medication list with the patient’s primary care doctor or community pharmacy, gaps form. Studies show 78% of errors during transitions come from missing or conflicting information between care settings.

Can electronic health records (EHRs) prevent medication errors?

EHRs can help reduce errors by 32% overall, but only if used correctly. During initial setup, they can actually increase discrepancies by 18% because staff rely on auto-filled lists without verifying them. The key is combining EHRs with human review-especially by pharmacists-and using them to support, not replace, clinical judgment.

Why is pharmacist involvement so important in discharge reconciliation?

Pharmacists are trained to spot drug interactions, duplicate therapies, and inappropriate dosing. Hospitals with dedicated transition pharmacists see 57% fewer post-discharge medication errors and 38% fewer readmissions. They also spend time asking patients if they understand their meds-something doctors rarely have time to do.

How long does it take to implement a successful medication reconciliation program?

It typically takes 6-9 months to fully implement a program that works. The AHRQ MATCH toolkit recommends a 12-step process, including staff training, role definition, and workflow redesign. Quick fixes-like just adding a form to the EHR-usually fail. Real change requires time, commitment, and teamwork.

What should patients do to protect themselves during discharge?

Bring a complete list of all medications-including supplements and OTC drugs-to every appointment. Ask: “What’s new? What’s changed? What should I stop?” Get a printed copy of your discharge meds before leaving. Follow up with your GP or pharmacist within a week to confirm everything matches. Don’t assume the hospital handled it.

tag: medication reconciliation discharge safety medication errors care transitions patient safety

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13 Comments
  • George Taylor

    George Taylor

    Ugh. Another one of these "we know the solution" posts. Yeah, sure. Just add more pharmacists. Like hospitals aren't already drowning in paperwork. And don't get me started on EHRs-those things are worse than a 2003 dial-up connection. I've seen nurses spend 45 minutes just trying to find a patient's meds. Meanwhile, the guy on the other side of the unit is coding. So yeah. "Preventable." Right.

    December 9, 2025 AT 01:17

  • Carina M

    Carina M

    It is, indeed, a profoundly concerning systemic failure that medication reconciliation remains an afterthought rather than a cornerstone of patient safety protocol. The absence of standardized, interoperable electronic health record integration across care continua represents not merely an operational inefficiency, but a moral lacuna in the delivery of evidence-based care. One cannot, in good conscience, permit the continued proliferation of preventable adverse drug events predicated upon clerical negligence and institutional inertia.

    December 10, 2025 AT 17:16

  • Ajit Kumar Singh

    Ajit Kumar Singh

    In India we dont have this problem because we dont have hospitals with EHRs at all. We have nurses who remember every patient’s meds by heart. Also we dont have 800k errors because we dont have 800k patients on blood thinners. But yes, if you have money to hire pharmacists, good for you. Here, we just give pills and pray. God is our last line of defense

    December 12, 2025 AT 16:42

  • Maria Elisha

    Maria Elisha

    I just got discharged last week and my pharmacist called me because my hospital sent the wrong dose. Like... why is this even a thing? I didn't even know I was supposed to be on two pills until I got home and my mom asked why I had three bottles. The system is just... broken. And nobody cares.

    December 14, 2025 AT 11:09

  • Angela R. Cartes

    Angela R. Cartes

    I mean... I get it. Pharmacists are amazing. But like... can we just admit that 90% of this is just making people do MORE work? 😩 I’ve seen the forms. The checklists. The ‘patient education’ packets. It’s just paperwork with a fancy name. And the patients? They’re too tired to care. Or confused. Or both. 😔

    December 15, 2025 AT 11:45

  • Sabrina Thurn

    Sabrina Thurn

    The data here is unequivocal: multidisciplinary reconciliation led by clinical pharmacists reduces readmissions by 38% and adverse drug events by 57%. This isn't anecdotal-it's validated across multiple RCTs and meta-analyses. The bottleneck isn't technology; it's workflow design and role ambiguity. The MARQUIS study demonstrated that when responsibility is unambiguously assigned to a pharmacist with protected time, compliance increases by 72%. EHRs are tools, not solutions. The real intervention is human expertise embedded in the discharge pathway-not bolted on as an afterthought.

    December 16, 2025 AT 05:28

  • Courtney Black

    Courtney Black

    It’s interesting how we’ve turned something as fundamentally human as remembering what pills someone takes into a bureaucratic ritual. We have machines that can predict heart attacks from a single ECG, but we still rely on a nurse asking a drowsy patient, "What did you take yesterday?" as if that’s enough. We’re not fixing systems-we’re just adding layers of formality to mask our failure to care. The truth? No algorithm, no checklist, no pharmacist-even the best one-can replace the simple act of listening. And we’ve forgotten how.

    December 18, 2025 AT 04:03

  • iswarya bala

    iswarya bala

    I work in a clinic in Delhi and we dont have time for all this but i can tell u one thing - if you ask patients to bring their pill bottles, they always show up. Even if they cant read. They know the color. The shape. The bottle. Thats real info. Not what's in the computer. So just ask. Please.

    December 18, 2025 AT 17:46

  • Simran Chettiar

    Simran Chettiar

    The philosophical underpinning of medication reconciliation lies not in procedural compliance, but in the ontological recognition of patient agency. To reduce a person’s pharmacological regimen to a static data point within an electronic health record is to deny their lived experience of illness, adaptation, and self-management. The most effective reconciliation occurs not when the system matches the list, but when the clinician acknowledges that the patient’s understanding of their own body supersedes institutional documentation. This is not a checklist-it is a covenant.

    December 19, 2025 AT 21:09

  • Anna Roh

    Anna Roh

    I read this whole thing and I’m still not sure what the actual fix is. Like, yes, pharmacists help. But how many hospitals can even afford that? And who’s gonna train them? And what about the ones that already have pharmacists but still mess up? It’s all just... noise.

    December 20, 2025 AT 09:41

  • om guru

    om guru

    Medication reconciliation is not a task it is a discipline. It requires leadership commitment structural change and cultural shift. The solution is not to add more people but to empower those already present. Assign responsibility. Protect time. Reward accuracy. Do this consistently and results will follow. No software required.

    December 20, 2025 AT 20:11

  • Philippa Barraclough

    Philippa Barraclough

    I find it fascinating how the most effective interventions-like pharmacist-led reconciliation or the MATCH toolkit-are low-tech, labor-intensive, and require deep human engagement. Meanwhile, hospitals pour millions into EHR upgrades that, as the JAMA study shows, often make things worse in the short term. It suggests a deeper cultural aversion to investing in people. We’d rather automate a broken process than redesign it around human behavior. The technology is ready. The will isn’t.

    December 22, 2025 AT 00:04

  • Tim Tinh

    Tim Tinh

    My grandma got discharged last year and they gave her 7 new meds. She didn’t know half of them. I had to call the pharmacy myself. The nurse said "it’s on the paperwork." But the paperwork was 4 pages of tiny font and half of it was wrong. I’m not mad. I’m just tired. We need to stop pretending this is just a "system issue." It’s a care issue. And we’re failing.

    December 22, 2025 AT 01:45

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